黒滝大翼研究室
熊本大学国際先端医学研究機構
免疫ゲノム構造学研究室
代表論文
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Komohara Y, Kurotaki D# (#co-first author), Tsukamoto H, Miyasato Y, Yano H, Pan C, Yamamoto Y, Fujiwara Y: Involvement of protumor macrophages in breast cancer progression and characterization of macrophage phenotypes. Cancer Sci 114(6):2220-2229, 2023. https://onlinelibrary.wiley.com/doi/full/10.1111/cas.15751
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Kurotaki D* (*corresponding author), Kikuchi K# (#co-first author), Cui K, Kawase W, Saeki K, Fukumoto J, Nishiyama A, Nagamune K, Zhao K, Ozato K, Rocha PP, Tamura T: Chromatin structure undergoes global and local reorganization during murine dendritic cell development and activation. Proc Natl Acad Sci USA 119(34): e2207009119, 2022. https://doi.org/10.1073/pnas.2207009119
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Kawase W, Kurotaki D* (*corresponding author), Suzuki Y, Ishihara H, Ban T, Sato GR, Ichikawa J, Yanai H, Taniguchi T, Tsukahara K, Tamura T: Irf5 siRNA-loaded biodegradable lipid nanoparticles ameliorate concanavalin A-induced liver injury. Mol Ther Nucleic Acids 25: 708-715, 2021.
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Kurotaki D* (*corresponding author), Yoshida H, Tamura T: Epigenetic and transcriptional regulation of osteoclast differentiation: Bone 138: 115471, 2020. Review
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Kurotaki D* (*corresponding author), Kawase W, Sasaki H, Nakabayashi J, Nishiyama A, Morse HC 3rd, Ozato K, Suzuki Y, Tamura T: Epigenetic control of early dendritic cell lineage specification by the transcription factor IRF8 in mice: Blood 133(17): 1803-1813, 2019. Selected as a Plenary Paper
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Izawa N, Kurotaki D# (#co-first author), Nomura S, Fujita T, Omata Y, Yasui T, Hirose J, Matsumoto T, Saito T, Kadono Y, Okada H, Miyamoto T, Tamura T, Aburatani H, Tanaka S: Cooperation of PU.1 with IRF8 and NFATc1 defines chromatin landscapes during RANKL-induced osteoclastogenesis. J Bone Miner Res 34(6): 1143-1154, 2019.
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Kurotaki D, Nakabayashi J, Nishiyama A, Sasaki H, Kawase W, Kaneko N, Ochiai K, Igarashi K, Ozato K, Suzuki Y, Tamura T: Transcription factor IRF8 governs enhancer landscape dynamics in mononuclear phagocyte progenitors. Cell Rep 22(10): 2628-2641, 2018.
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Kurotaki D, Sasaki H, Tamura T: Transcriptional control of monocyte and macrophage development. Int Immunol 29: 97-107, 2017. Review
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Kurotaki D* (*corresponding author), Tamura T: Transcriptional and epigenetic regulation of innate immune cell development by the transcription factor, interferon regulatory factor-8. J Interferon Cytokine Res 36(7):433-441, 2016. Review
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Kurotaki D* (*corresponding author), Uede T, Tamura T: Functions and development of red pulp macrophages. Microbiol Immunol 59(2):55-62, 2015. Review
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Sasaki H, Kurotaki D# (#co-first author), Osato N, Sato H, Sasaki I, Koizumi S, Wang H, Kaneda C, Nishiyama A, Kaisho T, Aburatani H, Morse HC 3rd, Ozato K, Tamura T: Transcription factor IRF8 plays a critical role in the development of murine basophils and mast cells. Blood 125(2):358-369, 2015.
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Kurotaki D, Yamamoto M, Nishiyama A, Uno K, Ban T, Ichino M, Sasaki H, Matsunaga S, Yoshinari M, Ryo A, Nakazawa M, Ozato K, Tamura T: IRF8 inhibits C/EBPα activity to restrain mononuclear phagocyte progenitors from differentiating into neutrophils. Nat Commun 5:4978, 2014.
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Kurotaki D, Osato N, Nishiyama A, Yamamoto M, Ban T, Sato H, Nakabayashi J, Umehara M, Miyake N, Matsumoto N, Nakazawa M, Ozato K, Tamura T: Essential role of the IRF8-KLF4 transcription factor cascade in murine monocyte differentiation. Blood 121(10):1839-1849, 2013.
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Kurotaki D, Kon S, Bae K, Ito K, Matsui Y, Nakayama Y, Kanayama M, Kimura C, Narita Y, Nishimura T, Iwabuchi K, Mack M, van Rooijen N, Sakaguchi S, Uede T, Morimoto J: CSF-1-dependent red pulp macrophages regulate CD4 T cell responses. J Immunol 186(4):2229-2237, 2011.
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Kanayama M, Kurotaki D# (#co-first author), Morimoto J, Asano T, Matsui Y, Nakayama Y, Saito Y, Ito K, Kimura C, Iwasaki N, Suzuki K, Harada T, Li HM, Uehara J, Miyazaki T, Minami A, Kon S, Uede T. J Immunol 182(12):8015-25, 2009.